Neuro-vascular central nervous recording/stimulating system: Using nanotechnology probes

نویسندگان

  • Rodolfo R. Llinás
  • Kerry D. Walton
  • Masayuki Nakao
  • Ian Hunter
  • Patrick A. Anquetil
چکیده

Electrical recording from spinal cord vascular capillary bed has been achieved demonstrating that the intravascular space may be utilized as a means to address brain activity with out violating the brain parenchyma. While the initial demonstration was implemented using electrically insulated platinum electrodes in vitro, the possibility of using conducting polymer filaments is now being explored. This paper presents a set of highly possible future scenarios where the integration of electrophysiology and novel polymer technology may serve as a new approach towards basic and medical neuroscience.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

iTRAQ-based proteomics profiling of Schwann cells before and after peripheral nerve injury

Objective(s): Schwann cells (SCs) have a wide range of applications as seed cells in the treatment of nerve injury during transplantation. However, there has been no report yet on kinds of proteomics changes that occur in Schwann cells before and after peripheral nerve injury.Materials and Methods: Activated Schwann cells (ASCs) and normal Schwann cells (NSCs) were obtained from adult Wistar ra...

متن کامل

Flexible Probes for in vivo Recording and Stimulation of Neural Tissue

Probing and stimulating neural tissue is important to understand fundamentals of information processing and pathologies of the nervous system such as Parkinson’s disease, epilepsy, or spinal cord injury. Therefore it is desirable to collect data from multiple recording sites with high resolution and specifically manipulate neuronal activity in the regions of interest. Moreover, unspecific inter...

متن کامل

Flexible Probes for in vivo Recording and Stimulation of Neural Tissue

Probing and stimulating neural tissue is important to understand fundamentals of information processing and pathologies of the nervous system such as Parkinson’s disease, epilepsy, or spinal cord injury. Therefore it is desirable to collect data from multiple recording sites with high resolution and specifically manipulate neuronal activity in the regions of interest. Moreover, unspecific inter...

متن کامل

O22: Principles of Treatment in Neuro-Inflammation Disorders

Treating Central Nervous System (CNS) neuro-inflammational disorders is of great importance. A key aspect of this treatment includes regulation of Cell-Mediated and humoral immune systems. Previous treatment mostly consisted of systemic immunosuppressive drugs. In addition to having adverse side effects, these drugs were also inefficient, such as methotrexate- Cyclophosphamide-Azathioprine. Rec...

متن کامل

[Neuro-glio-vascular interaction in ischemic brains].

The brain contains glial cells (astrocytes, microglia, and oligodendrocytes) and endothelial cells in addition to neurons. Under various pathologic conditions, the invasion of leukocytes such as neutrophils, monocytes/macrophages, and lymphocytes is observed. Interactions among these cell types play crucial roles both in brain function and dysfunction. However, the molecular basis of such inter...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005